December 14, 2007

TcLand Expression will attend GENESIS VII (UK’S largest biotechnology networking conference) in London.

November 26, 2007

TcLand Expression presented the Tclandscape technology at the annual congress of the SFI in Lyon.

Press Release	15/01/08	TcLand Expression SA and its partners, Nantes’ University Hospital, Atlanstat, and Nantes' "GIS Ouest Genopole" transcriptomics platform, today announced the creation of CIMNA, a unique integrated immunomonitoring service platform located in Nantes.
Press Release	14/12/07	TcLand Expression raises €8.2 million in a Series A round led by Auriga Partners.
Press Release	10/12/07	TcLand SA announces a company split into two autonomous branches of activity.
L'Expansion	01/07	Greffes: le risque de rejet anticipé.
La Tribune	22/01/07	TcLand a posé des remparts tout autour de ses brevets.
Press Release	29/08/06	TcLand strengthens its management team and Board of Directors
Press Release	02/06/06	Debiopharm and Tcland sign r&d and exclusive licence option for the development of sc28AT in autoimmune diseases and transplantation.
Press Release	15/06/05	Inserm-Transfert invests in TcLand

TcLandscape

Serial evolution of TCR b chain transcript mobilization in HIV-1 infected patients following vaccine immune stimulation and HAART interruption. M. Guillet, M. Andrieu, C. Braudeau, C. Ruiz, N. Daniel, A. Pallier, B. Charmeteau, J. Veziers, N. Oden, N. Bonilla, S. Brouard, J.G. Guillet and J.P. Soulillou. AIDS Research and Human Retroviruses. 2006. 648-56

Compartmentalization of TCR Repertoire Alteration during rejection of an intra brain xenograft. B. Melchior, V. Nerriere Daguin, S. Brouard, M. Guillet, J.P. Soulillou, P. Brachet. Experimental Neurology. 2005. 192:373.

Different patterns of TCRb chain regulation following Allo and Xeno transplantation. M. Guillet, S. Brouard, K. Gagne, D. Lair, J.M. Heslan, J.C. Doré, J.P. Soulillou. Xenotransplantation. 2004. 11:315.

Blood T cell Vb transcriptome in melanoma patients. N. Degauque, D. Schadendorf, S. Brouard, M. Guillet, F. Sébille, H. Höhn, A. Pallier, C. Ruiz, A. Dupont, S. Chapin, U. Hofmann, M. Maeurer, J.P. Soulillou. International Journal of Cancer. 2004. 110:721.

Different qualitative and quantitative regulation of Vb TCR transcripts during early acute allograft rejection and tolerance induction. M. Guillet, S. Brouard, K. Gagne, F. Sebille, M.C. Cuturi, M.A. Delsuc, J.P. Soulillou. The Journal of Immunology. 2002. 168:5088.

Direct Recognition of Foreign MHC Determinants by Naive T Cells Mobilizes Specific Vb Families Without Skewing of the ComplementarityDetermining Region 3 Length Distribution. F. Sebille, K. Gagne, M. Guillet, N. Degauque, A.Pallier, S. Brouard, B. Vanhove, M.A. Delsuc, J .P. Soulillou. The Journal of Immunology. 2001. 167:3082.

TCR usage in naive and committed alloreactive cells: Implications for the understanding of TCR biases in transplantation. M. Guillet, F. Sebille, J.P. Soulillou. Current Opinion in Immunology. 2001. 13:566–571.

Biomarkers

Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases. Patrick Miqueu, Marina Guillet, Nicolas Degauque, Jean-Christophe Doré, Jean-Paul Soulillou, Sophie Brouard. Mol Immunol. 2007. 44:1057-64.

Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Brouard S, Mansfield E, Braud C, Li L, Giral M, Hsieh SC, Baeten D, Zhang M, Ashton-Chess J, Braudeau C, Hsieh F, Dupont A, Pallier A, Moreau A, Louis S, Ruiz C, Salvatierra O, Soulillou JP, Sarwal M. PNAS. 2007. 15448-53

Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters. David-Axel Laplaud , Laureline Berthelot , Patrick Miqueu, Kasia Bourcier, Julien Moynard, Yannick Oudinet, Marina Guillet, Catherine Ruiz, Neal Oden, Sophie Brouard, Charles R.G. Guttmann, Howard L. Weiner, Samia J. Khoury, Jean-Paul Soulillou. J Neuroimmunol. 2006. 177:151-60.

Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation. S. Brouard, A. Dupont, M. Giral, S. Louis, D. Lair, C. Braudeau, N. Degauque, F. Moizant, A. Pallier, C. Ruiz, M. Guillet, D.A. Laplaud, J.P. Soulillou. American Journal of Transplantation. 2005. 5:330.